Baseline PSA as a predictor of prostate cancer-specific mortality over the past 2 decades
نویسندگان
چکیده
منابع مشابه
Free PSA as a Predictor of Prostate Cancer
Clinically diagnosed Prostate cancer is suspected due to raised PSA and abnormal DRE. DRE detected prostate cancer is often advanced and not amenable to curative treatment. The use of PSA as a serum marker has revolutionized PCa diagnosis. PSA is specific to the gland but not specific to cancer, therefore, it may be elevated in benign prostatic hypertrophy (BPH), prostatitis and other nonmalign...
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PSA is a 33-KDa serine protease that is produced predominantly by prostate epithelium. However, it has been shown that about 30-40% of female breast tumors produce PSA and its production is associated with the presence of estrogen and progesterone receptors. We have now developed a new tissue culture system to study PSA production in breast cancer and its association with prognostic factors...
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Introduction: Prostate cancer is one of the most common cancers in Iranian men. PSA(prostate specific antigen) screening is a controversial issue because PSA screening leads to diagnose of patients with low risk prostate cancer who not only do not benefit from treatment but also suffer from complication caused by treatment. On the other hand, without prostate cancer screening, the rate of meta...
متن کاملAssociation between prostate specific antigen change over time and prostate cancer recurrence risk: a joint model
Background: Prostate specific antigen (PSA) is an important biomarker to monitor patients after treated with radiation therapy (RT). The aim of this study is to evaluate the relationship between the PSA data and prostate cancer recurrence using the joint modeling. Methods: This historical cohort study was performed on 422 prostate cancer patients. Inclusion criteria included: patients with loc...
متن کاملDoes PSA screening reduce prostate cancer mortality?
question whether the recent decline in age-standardized prostate cancer mortality rates in Quebec could be attributed to screening with the serum prostate-specific antigen (PSA) test. By comparing the change in the incidence rate of prostate cancer between 1989 and 1993 with the change in the prostate cancer mortality rate between 1995 and 1999 in 15 birth cohorts, and in 15 regions of Quebec, ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2010
ISSN: 0008-543X
DOI: 10.1002/cncr.25447